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Blood analysis for L-carnitine derivatives showed that glutaryl carnitine and carnosyl carnitine were significantly decreased in ASD group and the authors of this publication suggested that those 2 compounds may be potential biomarkers for diagnosis of ASD

Pharmaceutical agents such as Cox-2 inhibitors, thalidomide, megestrol, medroxyprogesterone acetate, melatonin, and DCA, and supplemental nutrients or antioxidants from food [35], such as -3 poly-unsaturated fatty acids, vitamin C, vitamin D, vitamin E, -hydroxy--methylbutyrate (HMB) [36] and lycopene, represent potential anti-cachexia treatments that are being explored in clinical trials

TR Isoforms as Therapeutic Targets TR isoform agonists have been the primary target for drug development, especially for the treatment of hypercholesterolemia and obesity (270) ( Table 4 )

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