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Thus, necrotic death modalitiesRIP1/3-mediated necroptosis, mPTregulated necrosis and ferroptosisinduced by platinum-containing compounds and taxanes can improve the outcome of the anticancer chemotherapy
Peptides capable of binding copper ions have become an area of research due to their potential role in: Cellular signaling mechanisms Peptidemetal interactions Structural and biochemical modeling Tissue and extracellular matrix research models GHK-Cu is one of the most widely referenced copper peptides in scientific literature, making it a frequent subject of in vitro and ex vivo research
Additional studies have shown that orientin, dulaglutide, and dracorhodin inhibit ferroptosis by activating the Nrf2 pathway, thereby promoting diabetic wound healing [185,186,187]
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