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Description
doi: 10.1073/pnas.1716945115 45 GallusciP.AgiusD

Through establishing an interleukin (IL)-1-stimulated chondrocytes, it was found that L-theanine could inhibit the nuclear factor kappa B (NF-B) pathway, thereby reducing the expression of proinflammatory factors, including cyclooxygenase-2 (COX-2), prostaglandin E2, inducible nitric oxide synthase, as well as NO, and protect the degradation of extracellular matrix (29)

doi: 10.3390/ijms23094641 10

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