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Since this characteristic strongly correlates with tumorigenicity in animals [25], we hypothesized that interventions inhibiting TIC growth in 3D gels could also impede tumor development in vivo
In the FDA guidance on immunotoxicology evaluation, passive cutaneous anaphylaxis, active cutaneous anaphylaxis, and active systemic anaphylaxis assays have been used to predict type I reactions
doi: 10.1016/j.jaci.2017.02.036 111 GriffinJMHealyFMDahalLNFloisandYWoolleyJF
