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Th1 cells mainly mediate immune responses related to cytotoxicity and local inflammation, assist antibody production, and participate in cellular immunity and delayed hypersensitivity inflammation, while Th2 cells can assist B lymphocytes to differentiate into antibody-secreting cells and participate in humoral immune responses

doi: 10.1016/j.devcel.2019.10.007 54 AbramsRPCarrollWLWoerpelKA

Sodium stibogluconate loaded nano-deformable liposomes for topical treatment of leishmaniasis: macrophage as a target cell

[12] Other transgenic models have used other reporter genes such as enhanced green fluorescent protein (EGFP), tdTomato or luc to visualize senescent cell burden in vivo , as characterized by high expression levels of p16 or p21