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(4) Berberine reduces lipid peroxidation and inhibits ferroptosis by activating adenosine monophosphate-activated protein kinase in a renal ischemia-reperfusion mouse model, thereby alleviating kidney fibrosis (201)

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Physiol Rev 1031:276

Phase II takes the reactive metabolites from phase II and adds another molecule to make them safer and more water-soluble for elimination
