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Consistently positive results across these diverse injury models suggest the peptide works through fundamental mechanisms common to all wound healing rather than addressing only specific wound characteristics

NNMT is an enzyme that methylates nicotinamide (a form of vitamin B3), converting it to N1-methylnicotinamide and effectively removing it from the NAD+ salvage pathway

Notably, TILs demonstrate a progressive loss of mitochondrial mass and function ( Figure 6 )

[Put box around your final answer] 3 Potential (mV 400 300 -200 -100 0.0 100 200 300 400 500 600 700 800 0.99 0.98 0.98 0.95 0.95 0.90 0.85 0.81 0.77 0.71 0.65 0.31 0.12
