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This suggests that tesofensine may have two components: one anorexigenic and a second that stimulates energy expenditure, the latter perhaps mediated by its NE component [2, 61]

doi: 10.3389/fimmu.2025.1642942 Received 07 June 2025 Accepted 23 July 2025 Published 14 August 2025 Volume 16 - 2025 Edited by Nar Singh Chauhan, Maharshi Dayanand University, India Reviewed by Monika Yadav, Sanjay Ghodawat University, India Gulin Ozcan, Atilim University School of Medicine, Trkiye Naincy Rathee, Maharshi Dayanand University, India Updates Copyright 2025 Deng, Li, Liu and Wu

doi: 10.3389/fphar.2025.1689522 Received 28 August 2025 Accepted 08 October 2025 Published 23 October 2025 Volume 16 - 2025 Edited by Venkata Ramireddy Narala, Yogi Vemana University, India Reviewed by Yssel Mendoza-Mari, Western University of Health Sciences, United States Vira Zlatkina, V