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The optimal time for AOD-9604 administration is in a completely fasted state, typically first thing in the morning upon waking after an overnight fast of 8-10 hours
Western blot analyses confirm sustained ILK activity for 4-6 hours post-treatment in primary cardiomyocyte cultures
Single daily dosing suits general recovery and maintenance while split dosing at 0.25 mg every 12 hours maintains more consistent tissue levels beneficial for acute injuries
