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Embora interligado ao IGF-1, o IGF-1 Lr3 se diferencia por conter a arginina, o que justifica o nmero 3 na frmula

doi: 10.1038/nrclinonc.2013.46 186 DavilaMLRiviereIWangXBartidoSParkJCurranKet al

The relationship between peripheral and central OS markers is supported by evidence that glutathione and GSSG can cross the bloodbrain barrier through specific transporters [42]

It can also spare glycogen (the stored form of glucose) by providing an alternative energy source
