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Schisandrin A from Schisandra chinensis Attenuates Ferroptosis and NLRP3 Inflammasome-Mediated Pyroptosis in Diabetic Nephropathy through Mitochondrial Damage by AdipoR1 Ubiquitination
Antioxidant expression is either not induced or is declined, allowing increased ROS expression that positively promotes tubulointerstitial fibrosis via necrosis, apoptosis, epithelial-mesenchymal transition, interstitial fibroblast activation, endothelial cell proliferation, and pericytes transformation [17,209,229,230]

This will help healthcare providers make better choices

ROS can be a signaling molecule to cause DNA damage and apoptosis [40]
