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The viability and good health of naive GCLM knockout mice makes them a valuable model for studying the impact of chronic GSH deficiency 18

doi: 10.1371/journal.pone.0003394

It's gentler than hydroquinone but more effective than many natural skin brighteners like liquorice extract or vitamin C alone
The inhibition of nuclear factor kappa B is presumed to be the result of the binding of the selenium to the essential thiols of this transcription factor
