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B12 from food and supplements has to pass through a fairly involved process in the stomach and gut before your body can use it, and that process becomes less efficient with age, with certain medications, and with diets that include little or no animal protein

Requirement of ZO-1 for the formation of belt-like adherens junctions during epithelial cell polarization

Armstrong RC, Le TQ, Frost EE, Borke RC, Vana AC
