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To explore the microbial adaptation to, and functions in, this dietary shift in giant pandas, we investigated the microbial metabolic pathways in major nutrients (e.g., carbohydrate, amino acids) metabolism and compared them to mammals within three dietary patterns: herbivores (cattle and sheep), omnivores (pig, mouse, and human), and carnivores (cat) based on both metagenomic abundance and meta-transcriptomic expression

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These cancer stem cells are key drivers of cellular diversity and intratumor heterogeneity that drive cancer progression [72]