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Thiamine ( pyridoxine (B6) and cyanocobalamin (B12) are neurotropic substances and play a special role as coenzymes in intermediate metabolism in the central and peripheral nervous system

These animals were housed under controlled environmental conditions and had free access to food and water [1]

Note that in the majority of the participants, the weight loss obtained is well above 5% of the initial weight (the minimum associated with an improvement in health) and even exceeds 20% in many of them, in particular in the participants who received tirzepatide

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