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"It also can happen in adults when somebody is extremely stressed or they're maybe having a lot of difficulty with sleep schedule, changes or disruptions to their sleep." Other conditions, like sleep apnea, can lead to irregular sleep or sleep deprivation, and that may progress to a night terror, according to McGlinchey

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An increase in pathogenic bacteria such as Streptococcus and Moraxella can release pathogen-associated molecular patterns (PAMPs), which, in turn, trigger acute exacerbation of COPD ( In addition, high concentrations of PM 2.5 in the ambient air can accelerate the progression of COPD by increasing the abundance and variety of bacteria in the BALF of patients with stable COPD (65)