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We further hypothesized that supplementation with these metabolic cofactors would promote mitochondrial fatty acid uptake and oxidation, and reduce hepatic fat and inflammation, Zeybel said, adding that the underlying mechanism in the pathogenesis of NAFLD is inadequate removal of hepatic fat by fatty acid oxidation

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Several studies have shown that L-carnitine supplementation can lower the levels of total cholesterol, LDL cholesterol (bad cholesterol), and triglycerides in the blood

21,22 In one case, a 15-year-old male on valproic acid with a history of migraines, ADD, learning and behavioral problems acutely developed hyperammonemia and fatal cerebral edema OTC deficiency was diagnosed at autopsy