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A SYBR Premix Ex Taq (TaKaRa Bio, RR420A) was used to quantify the mRNA levels of related genes

Whilst B12 (cobalamin) is essential for nerve function, red blood cell production, and DNA synthesis, there is no established direct link between B12 supplementation and joint pain in medical literature

& Hellner, L

"Genetics are often the primary driver of premature graying but environment and lifestyle factors also play a role and can accelerate it." While optimizing glutathione and antioxidant levels can help, Lee said it won't compensate for systemic poor health including smoking, high alcohol intake and processed food-heavy diets