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Frank D, Savir S, Gruenbaum BF, Melamed I, Grinshpun J, Kuts R, et al

Patients with NTRK fusions should receive larotrectinib or entrectinib with serial ctDNA or tissue sequencing at progression to identify resistance mutations guiding selitrectinib-based salvage

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Keywords: Nucleic acid therapeutics, Nucleic acid drugs, Delivery systems, Nucleic acid delivery challenges, Lipid nanoparticle carriers Graphical abstract 1