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Description
Viral exosomes, EBER, protein S and SARS-CoV-2 intermediate dsRNAs activate TLRs receptors on endothelial cells of the blood-brain barrier, triggering the release of proinflammatory cytokines and altering barrier integrity (191193)

Plan experiments to minimize the number of freeze-thaw events
If injection frequency is a concern, MK-677 remains viable, but expect to fight more food cravings

As bacteriostatic water contains a bacteriostatic preservative, it can be used when multiple doses are required, as the vial can be stored for up to 28 days unlike sterile water, which is single-use and to be used immediately
