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In a few pathogens, including null-strains of Bordetella pertussis , Neisseria meningitidis and Haemophilus influenzae , the lipopolysaccharides lack an O-chain and are sometimes termed 'lipooligosaccharides' and tend to have more complex and highly decorated core structures that are responsible for bacterial specificity
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The pathophysiology of COVID-19-related brain damage is unclear, but it is linked to various mechanisms such as inflammation, oxidative stress, immune dysregulation, impaired glutamate homeostasis, glial and glymphatic damage, and hippocampal degeneration

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