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If cold sensations are particularly bothersome, your clinician or study team may consider adjusting the dose escalation schedule a common approach with GLP-1-based therapies where tolerability issues arise

In some cases, researchers prefer using a higher initial dose and lower maintenance doses

4.1.1 BCL family inhibitors The BCL family consists of proteins such as BCL-2, BCL-XL, and MCL-1, serving both proapoptotic and pro-survival functions [101]

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