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Description
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Cellular studies have shown that exogenous NAD + can impact mitochondrial activity, such as boosting Krebs cycle and the ETC, but also impair genomic DNA replication and induce DNA replication stress due to impairment of pyrimidine biosynthesis 118

Protocols typically run for 4 to 12 weeks, with extension as needed based on clinical response

It can also lead to nerve damage
