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Description
BPC-157 (Body Protection Compound-157) is a synthetic peptide consisting of 15 amino acids
Its molecular formula is C19H18O3, with a molecular weight of 294.33
doi: 10.1016/j.rx.2011.05.015
Gemtuzumab ozogamicin, the first approved ADC, primarily utilizes the acid-sensitive cleavage of the hydrazone linker to release cytotoxic agents, whereas the disulfide bond cleavage predominantly occurs during the intramolecular activation of N -acetyl--calicheamicin, which serves to maintain its molecular conformational stability rather than functioning as a release mechanism for the linker [124]
