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Studies have shown that ROS affect multiple inflammatory signaling pathways, including the nod-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome signaling pathway, NF-B signaling pathway, and MAPK signaling pathway (Fig

300 Mechanotransduction pathways such as the YAP/TAZ signaling pathways are activated in response to ECM stiffening, further reinforcing CSC plasticity and survival

To assess the possible mechanism of RGSH inhibition in AKI, a mouse AKI model and HK-2 cell ferroptosis model were built to perform in vitro and in vivo experiments

[DOI] [PMC free article] [PubMed] [Google Scholar] 204.Verma S., Anderson T.J
