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Description
535 A major site of proteostasis disruption in cancer is the ER, where high translational activity and secretory demands can easily overwhelm folding capacity
In this assay a damaged plasmid expressing a fluorescent protein reporter gene is transfected into the cells and the recovery of fluorescence detected by flow cytometry
Figure 1 3.1 N-acetylcysteine N-acetylcysteine (NAC), an essential precursor for GSH synthesis, is a critical brain antioxidant (Raghu et al., 2021)
Kosobokova EN, et al
