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First-in-human phase I trial of the PI3Kb-selective inhibitor SAR260301 in patients with advanced solid tumors (NCT01673737)
[DOI] [PubMed] [Google Scholar] 165.Nabot A., Omar F., Almousa M
Given the high hemoglobin content in RBCs, this mechanism likely operates in parallel, positioning CYB5R3 as a central regulator of both hemoglobin activity and NO signaling dynamics
