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Additionally, it has been found that AMPK, a cellular energy level sensor that is activated when ATP decreases and ADP or AMP increases in cancer, mediated the dysregulation of ACC phosphorylation to subsequently inhibit ACC activity, thus attenuating the lipogenesis of hepatoma cells (213)

Dihydro-5-azacytidine (DHAC) is a biologically active and chemically stable analog of 5-azacitidine with decreased toxicity

Furthermore, caspase signaling pathway would be activated to induce cell apoptosis and the development of kidney diseases (Sinha et al., 2013

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