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Figure 5 The generation of ROS by mitochondria is highly dependent upon mitochondrial membrane potential (m) and the amount of ROS produced can either trigger cellular proliferation (low ROS) or apoptosis (high ROS) (Martinez-Reyes and Cuezva, 2014)

Topper JN, Cai J, Falb D, Gimbrone MA Jr

Mitochondrial respiratory complex I dysfunction promotes tumorigenesis through ROS alteration and AKT activation

Bebb JR, Scott BB
