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The main limitations of these models are the low number of animals that can be generated and the high cost[219-221]

A strong argument can be made that all such tumors require a full thickness evaluation with permanent FFPE histology

Neuroscience and metabolic research: Earlier work found that melanocortin receptor activation by MT1 also touches on appetite, metabolism, and neurological signaling, areas that continue to attract interest as the broader melanocortin system is better understood
