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10.1089/ars.2015.6407 107 NakajimaS.KitamuraM

208 In 2016, the pyrazole compound 8 (APX-115 also known as Ewha-18278) was reported as a pan-NOX inhibitor ( K i of 1.08, 0.57, and 0.63 M for NOX1, NOX2, and NOX4, respectively) with no activity on xanthine oxidase or glucose oxidase

Chemico-Biological Interactions, 363 , 110019

While clinical ratings did not significantly differ between the intervention and placebo groups using the clinician-rated Ohio Autism Clinical Impressions Scale (OACIS), there were significant improvements in caregiver-reported measures of aberrant behaviors (ABC-2)
