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Informed Consent Statement Informed consent was obtained from all subjects involved in this study

The hCMEC/D3 cells were exposed to CQ, Zn 2+ , and Cu 2+ (collectively referred to as CZC at 0.5 mM, 0.5 mM, and 0.1 mM, respectively) for 24 h

An approach based on targeted elimination of senescent cells allows the body to reactivate its natural function without the need for artificial replacements

Collagen is the primary structural protein in connective tissue
