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Description
Antidepressants for neuropathic pain
HSP90 inhibitors such as ganetespib (STA-9090) and AUY922 have been extensively evaluated in oncology, 54,55 where they disrupt the stabilization of oncogenic client proteins
It does this by blocking the enzyme tyrosinase, which is involved in melanin production
Curr Opin Genet Dev 7:7579 Bourne HR, Sanders DA, McCormick F (1991) The GTPase superfamily: conserved structure and molecular mechanism
