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DPPC (1,2-dipalmitoyl-sn-glycero-3-phosphocholine) lipid was used for the preparation of neutral liposomes and a mixture of DOPE/DOTAP (1,2-dioleoyl-sn-glycero-3-phosphoethanolamine and 1,2-dioleoyl-3-trimethylammonium-propane) was used for cationic liposome preparation
Accordingly, the APAP-induced DILI model is the most prevalent experimental model in animal studies, effectively mimicking the intrinsic DILI toxicity mechanisms observed in humans [211]
Analysis of relative gene expression data using real-time quantitative PCR and the 2-[Delta][Delta] CT method
