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In a model of lung injury induced by amethopterin, carnitine has shown therapeutic potential by reducing the activities of P53 and CD68 while increasing the activity of Bcl-2 [310]

Acknowledgements This research was funded by National Basic Research Program of China (973 program 2014CB138600), National Natural Science Fund (31272676 and 31472290), and Program for New Century Excellent Talents in University

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To investigate mitochondrial dynamics, cells were transfected with the GFP-Mito plasmid previously used in the study [27] for 24 h, followed by an additional 24 h treatment with BSA alone or BSA-PC