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This is not a conservative precaution

Therefore, mitochondrial dysfunction would be expected to increase the reducing potential of a cell along with greater availability of free oxygen, which could result in the generation of ROS and oxidative stress (43, 72, 73, 99)

In the transsulfuration pathway, Hcy converts to cystathionine with the help of cystathionine--synthase (CBS)

Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) guidance in development (GID-NG10434)