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Clinical data show that continuous use of L-Carnitine Cream for 8 weeks can reduce local fat thickness by 12%-18% and shrink waist circumference by 2-3 cm

Microneedle introduction, liposome encapsulation or chemical penetration enhancers (such as azone) can increase its transdermal absorption rate to 15%-25%, bringing the local concentration to the effective threshold (5-10 mM)

Future Research Directions Nanocarrier technology: The development of nanoparticles or liposomes targeting adipocytes can significantly increase the subcutaneous retention time and bioavailability of L-carnitine