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J.FraiseA

receives grants from the Italian Ministry of Education, Universities and Research (MIUR, ref PRIN 2015, 2015FNWP34-002) and the Dystonia Medical Research Foundation and received honoraria and financial support to speak or attend meetings from AbbVie, Teva and Union Chimique Belge

A nanovaccine formulated using pH-responsive amphiphilic diblock copolymers synthesized via reversible addition-fragmentation chain transfer (RAFT) polymerization, conjugated with STING agonist ADU-S100 and mannose as well as further combined with antigen peptides and polyethyleneimine, can effectively inhibit tumor growth by specifically targeting DCs and efficiently activating them to promote antigen presentation (102)