can depression get worse after b12 injections permanent side effects supplementing B12? : r/B12_Deficiency Why do I feel worse
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How its given and how often is very important for treatment

Before taking, speak with your doctor if you are allergic to vitamin b12, have a genetic condition called optic atrophy, have blood in your urine, polycythemia, an ongoing infection, low iron or folate levels, are pregnant or plan to become pregnant, are breastfeeding or plan to breastfeed
the true usefulness of serum vitamin B12 levels

Cui Y, Yang D, Wang W, Zhang L, Liu H, Ma S, Guo W, Yao M, Zhang K, Li W (2020) Nicotinamide N-methyltransferase decreases 5-fluorouracil sensitivity in human esophageal squamous cell carcinoma through metabolic reprogramming and promoting the Warburg effect