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The reason is practical: fewer steps mean fewer opportunities for confusion
What are the potential side effects
Chakraborty S, Morganti C, Dey J, Zhang H, Aluri S, Gitego N, Pradhan K, Rivera B, Chutake Y, Skwarska A, Mantzaris I, Goldfinger M, Feldman EJ, Choudhary GS, Hubner S, Qiu Y, Brown BD, Verma A, Gavathiotis E, Konopleva MY, Kornblau SM , Gollob J, Ito K, Shastri A
doi: 10.1056/NEJMra1100359
