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These therapeutic effects correlated with preservation of both blood and spinal cord GSH levels in comparison to untreated transgenic controls, indicating that Immunocal is able to act directly on the CNS to preserve GSH status in the context of neurodegenerative disease

At the transcriptional level in kidney tubular epithelial cells, glutamine supplementation can downregulate proapoptotic genes (Harakiri [HRK] and BAD) and regulate cytoprotective genes (sulfiredoxin 1 [SRXN1] and heme oxygenase 1 [HMOX1])

V H and/or V L sequences provided herein Fabs and (Fab') 2 dimers can also readily be prepared
