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A study showed that the low-dose Carfilzomib-Bortezomib combination amplifies antitumor effects through ROS-dependent apoptosis and ER stress, reducing Bortezomib-related toxicity

This phenomenon may be linked to an altered ratio in anti-apoptotic and pro-apoptotic proteins

The bulk RNA-seq set from the GEO database demonstrates that CP expression is increased in the PD brain
