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There is growing consensus regarding their pathophysiology and management, but more work is needed to elucidate the relationships between irAEs and treatment outcomes, specific biomarkers that clinch an irAE diagnosis, the impact of tailored immunosuppression on ICI outcomes, and the management of steroid-refractory irAEs
Physiological limits to zinc bio-fortification of edible crops
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Spastic events are often velocity dependent, meaning the faster a limb is moving, the harsher the contraction, and this can cause feedback loops of spastic jerking during voluntary movement
