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It was evidenced in the current study that seed extract and L-dopa have the potential to ameliorate neuronal apoptosis by regulating the PI3K/Akt signalling pathway and its consequence on the molecular targets forkhead box transcription factor and glycogen synthase kinase 3, in addition to deflecting neurodegenerative diseases like Parkinsons caused by induced neurotoxicity

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Furthermore, the practical applicability of pGP/AuG is evaluated, in which 209 N-glycosylated peptides corresponding to 128 N-glycosylated proteins are identified from 1 L human serum in three independent analysis procedures, suggesting the great potential for application in glycoproteome fields.Graphical abstract