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In women with PMOS, kisspeptin signalling is dysregulated
doi: 10.31989/ffhd.v13i4.1093 62 TavasoliSJalaliSNajiMBorumandniaNMajdGSBasiriAet al
Explains how glutathione influences melanogenesis by shifting the balance from darker eumelanin to lighter pheomelanin via inhibition of tyrosinase (by copper chelation and antioxidant effect)
Therefore, electron microscopy is considered essential in the diagnostic work-up of pediatric liver biopsies, given that ultrastructural mitochondrial abnormalities help to distinguish WD from NAFLD and autoimmune hepatitis [28]
