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Upon activation by histamine typically released from mast cells or basophils, H1R mediates key physiological responses associated with inflammation and allergic reactions
Ulcerative Colitis (UC): Affects the colon and rectum , causing continuous inflammation along the intestinal lining, which can lead to ulcers, bleeding, and diarrhea

The big challenge is that gluten is contained in numerous foods and people also come into contact with it unintentionally
