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These elements and binding sites are activated by various harmful stimuli, including heavy metals, cytokines, inflammation, ischemia, heat shock, hypoxia, and oxidative stress

Considering this, therapeutic interventions incorporating substances possessing antioxidant and anti-inflammatory properties may be considered

Aging 102 , 211.e1211.e9 (2021)
They are small artificial fluid filled sacs, spherical in shape that are be created from natural non-toxic phospholipids to encapsulate and transport nutrients 26
