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H, 4.64

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Second, proteostasis disruption involves declined autophagylysosomal and ubiquitinproteasome activity, rendering proteins like syn prone to aggregation and resistant to clearance [62]

5 l of 10% trifluoroacetic acid (TFA, cas 76-05-1, Sigma Aldrich, #302031) was added to each sample to quench the reaction
