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[DOI] [PMC free article] [PubMed] [Google Scholar] 118.Heusch G

Furthermore, expression of GSH peroxidase and thioredoxin reductases were decreased in THCA tissue, indicating that the imbalance of the oxidant/antioxidant system played an important role in THCA (12)

Following this discovery, new 5-ASA formulations were developed to limit small bowel absorption and enhance colonic delivery [19]

The factor contributing to this is that the phase is most crucial as it involves 300-3000 participants and has a longer treatment period
