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Sifalimumab, a human anti-interferon- monoclonal antibody, in systemic lupus erythematosus: a phase 1 randomized controlled, dose-escalation study

As a comparison, in vitro enzyme activity-based metabolomics profiling represents one of the most common experimental technologies for discovering previously unknown metabolic reactions 12,17
(11) T J Smith (2010) Insulin-Like Growth Factor-I Regulation of Immune Function: A Potential Therapeutic Target in Autoimmune Diseases

Polyunsaturated fatty acids (PUFAs), including arachidonic acid (ARA) and its metabolites, have been shown to regulate the transfer of cholesterol from the outer to the inner membrane of mitochondria
